Magnetotherapy: Instead of having a morphine injection for intense pain, determine the magnetic pattern that stimulates release of an equivalent dose of endogenous opioids

e.g. 1 s of 5 x 10 μT every 4 s for 20 min

 

The electricity pattern that powers body chemistry can be coded by/equates a time-varying magnetic pattern

 

The authors of this Science study, Lewis, J. W., Cannon, J. T. and Libeskind, J. C.: Opioid and nonopioid mechanisms of stress analgesia, Science 208, 623-625,1980 did foot electroshock on rats and found out that the rats were somehow less active than control animals as measured from their tale flicking.

 

This electroshock not only does it not induce pain (algos), on the contrary, it induces as antalgic (anti-pain response). The scientists followed two stimulation mechanisms: (i) continuous foot shock for 3 minutes; (ii) prolonged, intermittent foot shock for 30 minutes (1-second pulses delivered every 5 seconds).

 

Interestingly, the intermittent stimulation produced a much stronger antalgic response.

 

Which molecule could be the mediator? Endogenous opiods?

 

Do you know that acupuncture reduces pain and that this action is reduced if you remove the hypophysis? The latter produces ACTH and endorphins. Could ACTH or endorphins be the mediator for analgesia?

 

The scientists used an inhibitor for opioids and an inhibitor for ACTH (which however also inhibits opioids). Both inhibitors cancelled antalgic responses for the intermittent stimulation but not for the continuous one.

 

It is concluded that each stimulation pattern activates different analgesia mechanisms. Specifically, the intermittent foot stimulation of 1-second pulses delivered every 5 seconds activates opioid analgesia mechanisms.

 

Similar study cited for stress: Amir S, Amit Z. Endogenous opioid ligands may mediate stress-induced changes in the affective properties of pain related behavior in rats. Life Sci. 1978 Sep 18;23(11):1143–1151. [PubMed] [Full text here]

 

The authors of the study J L. Fleming, M. A. Persinger, and S A. Koren. Magnetic pulses elevate nociceptive thresholds: comparisons with opiate receptor compounds in normal and seizure-induced brain-damaged rats. ELECTRO- AND MAGNETOBIOLOGY, 13(1), 67-75 (1994) available in full text here found out that:

delivery of weak (5 x 10μΤ) magnetic fields for 1s every 4s produces an analgesic effect, and by referring to the study descrived above, they mention that this effect is “comparable to more noxious tactile stimulation through somatic sensors (3).”

 

Here is an interesting review on “Emerging synergisms” between Drugs and Magnetic Therapy

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644491/

Emerging Synergisms Between Drugs and Physiologically-Patterned Weak Magnetic Fields: Implications for Neuropharmacology and the Human Population in the Twenty-First Century

 

Here is a review on Magnetic Therapy

http://www.curatron.com/pdf/PEMF_therapeutic_uses.pdf

Therapeutic uses of Pulsed Magnetic-Field Exposure: A review

 

 

Related to this study is the post:

"On the possibility of human brain access by electromagnetic induction of fundamental algorithms"

Link